Progress in the Application and Scheme of the Ketogenic Diet in the Treatment of Metabolic Diseases

LI Yuqi; ZHOU Yongbo; SHAN Yongjun; HUANG Shiying; ZHOU Lixin; LI Jian

doi:10.13386/j.issn1002-0306.2022120148

Volume 44 Issue 22

Nov. 2023

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Science and Technology of Food Industry > 2023 > 44(22): 352-359. > DOI: 10.13386/j.issn1002-0306.2022120148

LI Yuqi, ZHOU Yongbo, SHAN Yongjun, et al. Progress in the Application and Scheme of the Ketogenic Diet in the Treatment of Metabolic Diseases[J]. Science and Technology of Food Industry, 2023, 44(22): 352−359. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022120148.

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Progress in the Application and Scheme of the Ketogenic Diet in the Treatment of Metabolic Diseases

LI Yuqi^1,,
ZHOU Yongbo^{1, 2},
SHAN Yongjun³,
HUANG Shiying¹,
ZHOU Lixin⁴,
LI Jian^{1, 2, ,}

1.
College of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China
2.
Fujian Provincial Engineering Technology Research Center of Marine Functional Food, Xiamen 361021, China
3.
Dazhou Xinyan Biotechnology Co., Ltd., Xiamen 361006, China
4.
The Second Affiliated Hospital of Xiamen Medical College, Xiamen 361021, China

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Received Date: December 17, 2022
Available Online: September 11, 2023

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Abstract

Abstract

Ketogenic diets have been shown to play a role in some metabolic diseases and neurodegenerative diseases as a low-carbohydrate, high-fat diets supplemented with appropriate protein. Ketogenic diets have been proven effective, but the mechanisms of action are still unclear. Therefore, this paper summarizes the development of the ketogenic diet, its application in the treatment of metabolic diseases (type Ⅱ diabetes, obesity, non-alcoholic fatty liver disease, and gout), recommended diet plans and adverse reactions, and confirms that the ketogenic diet can be used as an adjunct therapy for metabolic diseases in terms of improving stress response and the intestinal microbiome. The classic ketogenic diet, medium-chain triglyceride, modified Atkins diet, and low glycemic index treatment are recommended as ketogenic diet programs. The adverse reactions of the ketogenic diet in metabolism, gastrointestinal tract, urinary system, and contraindications are summarized. This paper also summarizes the invention patents of ketogenic diet-related products, which paved the way and prospected for the subsequent product development and as an auxiliary treatment program.
- ketogenic diet,
- metabolic diseases,
- mechanism of action,
- diet plan

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References (88)

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Science and Technology of Food Industry

Progress in the Application and Scheme of the Ketogenic Diet in the Treatment of Metabolic Diseases

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