Advances in Preparation, Biological Effect and Structure-activity Relationship of Hypoglycemic Peptides

ZHANG Tingxin; LI Fuqiang; ZHANG Nan; ZHU Liping; YAN Shigan

doi:10.13386/j.issn1002-0306.2021040219

Volume 43 Issue 8

Apr. 2022

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Science and Technology of Food Industry > 2022 > 43(8): 433-442. > DOI: 10.13386/j.issn1002-0306.2021040219

ZHANG Tingxin, LI Fuqiang, ZHANG Nan, et al. Advances in Preparation, Biological Effect and Structure-activity Relationship of Hypoglycemic Peptides[J]. Science and Technology of Food Industry, 2022, 43(8): 433−442. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021040219.

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Advances in Preparation, Biological Effect and Structure-activity Relationship of Hypoglycemic Peptides

Key Laboratory of Microbial Engineering of Shandong Province, School of Bioengineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China

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Received Date: April 25, 2021
Available Online: January 18, 2022

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Abstract

Diabetes is a serious global health problem, and its incidence rate has been increasing in recent years. Many drugs have been proven effective in the treatment of diabetes mellitus, but most of them have toxic side effects. Therefore, the development of safe and effective hypoglycemic drugs have drawn increasingly more attention around the world. Hypoglycemic peptides has the hypoglycemic effect and has little side effects, and has the research value in the field of functional food and drugs, and has a broad application prospect. In this paper, the preparation, biological effect and structure-activity relationship of hypoglycemic peptides in recent years are reviewed, and the research prospect of hypoglycemic peptides is looked forward, in order to provide reference for the development and utilization of hypoglycemic peptides and the further processing of related products.
- diabetes,
- hypoglycemic peptides,
- preparation,
- biological effects,
- structure-activity relationship

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