The bioactive of collagen peptides from jellyfish

Proteolysis of jellyfish waste materials were carried out with proteases to obtain antioxidant peptides. And then the bioactivities of different molecular weight fractions of jellyfish collagen peptides(JCP1>10 kDa>JCP2>3 kDa>JCP3>1 kDa>JCP4)prepared by ultrafiltration were evaluated.The result showed that JCP1 showed the highest rates to scavenge super oxide anion free radicals and inhibit tyrosinase activity,with the IC₅₀ values of 22.6 and 11.96 mg/mL,respectively. JCP3 presented the highest capacities of hydroxyl and ABTS free radical-scavenging activities,reducing power and ACE inhibitor activity,while the IC₅₀ values were 14.9,2.21,0.61 and 15.8 mg/mL respectively. JCP4 exhibited the best performance on DPPH free radical-scavenging activity(IC₅₀ of 28.3 mg/mL).