Study on tolerance characteristics of the gastrointestinal tract and cholesterol-lowering effects of Lactobacillus plantarum Zhang-LL

The tolerance characteristics of the gastrointestinal tract and cholesterol- lowering effects of Lactobacillus plantarum Zhang- LL isolated from fermented rice noodles in Bama,Guangxi Province were investigated. Viable count was firstly used in this study to detect the tolerance characteristics under simulated gastrointestinal tract environment p H1.5~ 3.0. Additionally,bacterial growth was evaluated in the presence of 0.10% ~ 0.50% bile salt.O- phthalaldehyde was used to detect its cholesterol- lowering capability. The results showed that Lactobacillus plantarum Zhang-LL's number of viable bacteria was still up to 106 CFU / m L after 3 h under p H1.5~ 3.0,whose initial bacterial count was 1 × 107 CFU / m L. And being cultured for 8 h in the MRS- broth( 0.10% ~ 0.50% bile salt),the viable count reached nearly to 105~ 107 CFU / m L. A cholesterol removal rate ranging from 20.69% to 35.68% was observed under varying conditions.It showed that Lactobacillus plantarum Zhang- LL had a strong capability of anti gastric intestinal reverse environment and good cholesterol lowering ability,which provided the experimental basis for the development of cholesterol- lowering functional food and micro ecological preparation.