Ultrasonic- assisted extraction of total flavonoids from Michelia Alba leaves using response surface methodology
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Department of Food and Biology Engineering,Zhangzhou Institute of Technology
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College of Biological Science and Technology,Minnan Normal University
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Applied Technology Engineering Center of Fujian University for Further Processing and Safety of Agricultural Products
More Information
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- Received Date:
January 13, 2016
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Abstract
The ultrasonic- assisted extraction conditions of polyphenol from michelia alba leaves were optimized by response surface methodology.Based on single factor test,a 4- factor,3- level Box- Behnken experimental was adopted including dependent variables( ethanol concentration,liquid to material ratio,ultrasonic time and ultrasonic temperature) and independent variable( yield of polyphenols). The results showed that the optimum conditions were ethanol concentration 54%,liquid to material ratio 19 m L / g,ultrasonic time 25 min,ultrasonic temperature66 ℃. The yield of total flavonoids could be up to 9.94% under the optimal extraction condition,the relative error was 0.30% compared to the predictive value,which indicated the feasible model fitted well with the experimental data.The research could be developed a theoretical foundation and a scientific basis for the extraction of total flavonoids from michelia alba leaves into natural antioxidant.
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References
| [1] |
H M Wang,W L Lo,L Y Huang,et al.Chemical constituents from the leaves of Michelia alba[J].Natural Product Research,2010,24(5):398-406.
|
| [2] |
E Q Xia,Y Song,X X Ai,et al.A new high-performance liquid chromatographic method for the determination and distribution of linalool in Michelia alba[J].Molecules,2010,15(7):4890-4897.
|
| [3] |
C Shang,Y Hu,C Deng,et al.Rapid determination of volatile constituents of Michelia alba flowers by gas chromatographymass spectrometry with solid-phase microextraction[J].Journal of Chromatography A,2002,942(1):283-288.
|
| [4] |
C Y Chen,L Y Huang,L J Chen,et al.Chemical constituents from the leaves of Michelia alba[J].Chemistry of Natural Compounds,2008,44(1):137-139.
|
| [5] |
J I Dower,J M Geleijnse,L Gijsbers,et al.Effects of the pure flavonoids epicatechin and quercetin on vascular function and cardiometabolic health:a randomized,double-blind,placebocontrolled,crossover trial[J].The American Journal of Clinical Nutrition,2015,101(5):914-921.
|
| [6] |
M Funakoshi-Tago,K Okamoto,R Izumi,et al.Antiinflammatory activity of flavonoids in Nepalese propolis is attributed to inhibition of the IL-33 signaling pathway[J].International Immunopharmacology,2015,25(1):189-198.
|
| [7] |
H Li,Q Lu,K Bian.Ultrasonic-assisted extraction and evaluation of biological activities of flavonoids from Flemingia philippinensis Merr et Rolfe[J].Tropical Journal of Pharmaceutical Research,2015,14(8):1365-1371.
|
| [8] |
陈建福,施伟梅.响应面法优化纤维素酶辅助提取西兰花总黄酮[J].四川农业大学学报,2014,32(3):298-304.
|
| [9] |
X Wang,Q Wu,Y Wu,et al.Response surface optimized ultrasonic-assisted extraction of flavonoids from Sparganii rhizoma and evaluation of their in vitro antioxidant activities[J].Molecules,2012,17(6):6769-6783.
|
| [10] |
B Liu,Y Ma,Y Liu,et al.Ultrasonic-assisted extraction and antioxidant activity of flavonoids from Adinandra nitida leaves[J].Tropical Journal of Pharmaceutical Research,2014,12(6):1045-1051.
|
| [11] |
H M Jin,X H Tan,W Cai,et al.Optimization of extraction technology of total flavonoids from Ampelopsis grossedentata using response surface methodology[J].Journal of Food Safety and Quality,2015,6(5):1575-1582.
|
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