Comparison of UPLC-MS/MS and HPLC for determination of 10 carbamate pesticide residues of tea

The ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) and high performance liquid chromatography (HPLC) for determination of 10 carbamate pesticide residues of tea were compared. The samples were extracted with acetonitrile, and cleaned up by amino solid-phase extraction column, then determined by HPLC and UPLC- MS / MS. The results showed that, both methods had good accuracy and precision. The recoveries ranged 75.2%¹15.6% by UPLC-MS/MS when spiked levels 0.01⁰.1mg/kg, with the relative standard deviations 4.4% ¹6.7%. The recoveries ranged 82.7% ¹20.7% by HPLC when spiked levels 0.05¹.0mg/kg, with the relative standard deviations 0.8%¹2.9%. UPLC-MS/MS had higher sensitivity, compared to HPLC, LOD of 10 carbamate pesticides on UPLC-MS/MS was 0.02⁰.3μg/kg, which on HPLC was 3⁷.5μg/kg. UPLC-MS/MS was more suitable for detection of multiple pesticide residues and trace pesticides because its high sensitivity and selectivity.