Study on extraction and bacteriostatic activities of flavonoids from Choerospondias axillaris peel

To optimize the process for flavonoids extraction from Choerospondias axillaris peel, a series of single -factor experiments were made to investigate the effects of ethanol concentration, extraction time and temperature, solid-to-liquid ratio on flavonoids yield, and based on this, response surface methodology (RSM) was applied to optimize the extraction conditions of flavonoids. The optimal extraction conditions were found to be:ethanol concentration of 60% and solid-to-liquid ratio of 1:25 for extraction duration of 1. 6h at 65℃. Under these conditions, the yield of flavonoids was 9. 72%. The bacteriostatic activities of extracts on foodborne pathogen were investigated. The extracts had better inhibition effects on gram positive bacteria than gram negative bacteria.