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中国精品科技期刊2020

菊糖面包对STZ糖尿病小鼠血脂、血糖的影响

熊政委, 董全, 王强

熊政委, 董全, 王强. 菊糖面包对STZ糖尿病小鼠血脂、血糖的影响[J]. 食品工业科技, 2015, (20): 368-370. DOI: 10.13386/j.issn1002-0306.2015.20.067
引用本文: 熊政委, 董全, 王强. 菊糖面包对STZ糖尿病小鼠血脂、血糖的影响[J]. 食品工业科技, 2015, (20): 368-370. DOI: 10.13386/j.issn1002-0306.2015.20.067
XIONG Zheng-wei, DONG Quan, WANG Qiang. Effect of inulin bread on blood glucose and lipid of mice with diabetes induced by STZ[J]. Science and Technology of Food Industry, 2015, (20): 368-370. DOI: 10.13386/j.issn1002-0306.2015.20.067
Citation: XIONG Zheng-wei, DONG Quan, WANG Qiang. Effect of inulin bread on blood glucose and lipid of mice with diabetes induced by STZ[J]. Science and Technology of Food Industry, 2015, (20): 368-370. DOI: 10.13386/j.issn1002-0306.2015.20.067

菊糖面包对STZ糖尿病小鼠血脂、血糖的影响

基金项目: 

国家“863”计划项目(2011AA100805-2);

详细信息
    作者简介:

    熊政委(1989-),男,硕士研究生,研究方向:食品安全与质量控制,E-mail:842406970@qq.com。;

    董全(1962-),男,博士,教授,研究方向:现代食品加工理论与技术,E-mail:dongquan@swu.edu.cn。;

  • 中图分类号: TS213.21;TS201.4

Effect of inulin bread on blood glucose and lipid of mice with diabetes induced by STZ

  • 摘要: 用链脲佐菌素(STZ)诱导成功的糖尿病小鼠为动物实验模型,将小鼠分为模型组、普通面包组、各种不同添加量(2%、4%、6%、8%、10%)的菊糖面包组,连续喂食15 d,研究血糖、总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白、体重的变化情况。结果表明,菊糖能够缓解STZ糖尿病小鼠体重的下降,降低STZ糖尿病小鼠的血糖值,并且对高脂血症有一定的调节作用,同时随着菊糖面包中菊糖含量的增加,其作用效果也得到增强。 
    Abstract: As animal models,diabetic mice were successfully induced by using the STZ. These mice divided into model group,ordinary bread group,variety of different amounts of inulin bread group(2%,4%,6%,8%,10%),feeded 15 days,studied the changes of blood glucose,total cholesterol,triglycerides,HDL,LDL,body mass.The results showed that the inulin could alleviate weight drops of STZ diabetic mice,lowered blood glucose levels in STZ diabetic mice,and had a certain adjustment of hyperlipidemia. At the same time,with the increase of the inulin content in the bread,the effect was improved.
  • [1] 曾小宇,罗登林,刘胜男,等.菊糖的研究现状与开发前景[J].中国食品添加剂,2010(4):222-227.
    [2] 崔钰,李超,钱川军,等.芦根多糖对糖尿病小鼠糖脂代谢调节的研究[J].农业机械,2012(24):142-144.
    [3] 勾向博,白静,姜妍,等.荞麦糠皮提取物对Ⅱ型糖尿病大鼠血糖和血脂的影响[J].食品科学,2013,34(1):303-305.
    [4]

    Ren J,Davidoff A J.Diabetes rapidly induces contractive dysfunctions in isolated ventricular myocytes[J].Am J Physiol,1997,272(1):148-158.

    [5]

    Yang HY,Yang SC,Chao JC,et al.Beneficial effects of catechin-rich green tea and inulin on the body composition of overweight adults[J].British Journal of Nutrition,2012,107(5):749-754.

    [6]

    Lee Cole LL,Hee WL,Berdine MR,et al.Prebiotics Enhance Magnesium Absorption and Inulin-based Fibers Exert Chronic Effects on Calcium Utilization in a Postmenopausal Rodent Model[J].Journal of Food Science,2012,77(4):88-94.

    [7]

    Tako E,Glahn RP.Intra-amniotic administration and dietary inulin affect the iron status and intestinal functionality of irondeficient broiler chickens[J].Poultry Science,2012,91(6):1361-1370.

    [8]

    Rault N,Marie H.Inulin attenuates atherosclerosis in apolipoprotein E-deficient mice[J].The British Journal of Nutrition,2006,96(5):840-844.

    [9]

    Beylot M.Effects of inulin-type fructans on lipid metabolism in man and in animal models[J].The British Journal of Nutrition,2005,93(S1):163-168.

    [10] 崔钰,李超,尤健,等.白茅根多糖改善糖尿病小鼠糖脂代谢作用的研究[J].食品科学,2012,33(19):302-305.
    [11] 严奉伟,严赞开,王辰,等.菜籽多糖对四氧嘧啶致糖尿病小鼠降血糖作用的研究[J].食品研究与开发,2007,28(3):11-14.
    [12] 宗灿华,于国萍.黑木耳多糖对糖尿病小鼠的降血糖作用[J].食用菌,2007,29(4):60-61.
    [13] 罗存敏.桑叶提取物对小鼠血糖血脂的影响及有效成分的测定[D].泰安:山东农业大学,2005.
    [14] 赵立,苟萍,王霞,等.大蒜活性物质对高脂小鼠血脂代谢的影响[J].中成药,2013,35(1):28-32.
    [15]

    Ooi L G,Ahmad R,Yuen K H,et al.Lactobacillus acidophilus CHO-220 and inulin reduced plasma total cholesterol and low-density lipoprotein cholesterol via alteration of lipid transporters[J].Journal of Dairy Science,2010,93(11):5048-5058.

    [16] 张明淘,顾显红,杨琳.菊粉的原生素作用研究进展[J].动物营养学报,2003,15(4):12-18.
    [17]

    Morris C,Morris G A.The effect of inulin and fructooligosaccharide supplementation on thetextural,rheological and sensory properties of bread and their role in weight management:A review[J].Food Chemistry,2012,133(2):237-248.

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  • 收稿日期:  2015-01-15

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