Research progress in emulsification/internal gelation technology for the preparation of alginate microcapsules
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摘要: 内源乳化法是近年来兴起的一种海藻酸盐微胶囊制备方法,在制备过程中使用的都是无毒试剂和溶剂,可在生物、食品、医药等行业中用于包埋生物活性物质。本文着重介绍了内源乳化法制备海藻酸盐微胶囊的原理,比较了内源乳化法与外源乳化法的异同,分析了制备过程中影响微胶囊性质的因素,归纳了近年来其在生物活性物质包埋中的应用,并展望了内源乳化法制备海藻酸盐微胶囊的发展前景。Abstract: Emulsification/internal gelation is a newly developed method for encapsulation in recent years. As all reagents and solvents used during the microcapsule preparation are nontoxic, the emulsification / internal gelation method has been adapted to encapsulate sensitive bioactive substances in biotechnology, food and medicine industries. In this paper, it was described the encapsulation mechanism of emulsification/internal gelation, compared these differences between emulsification/internal gelation and emulsification/external gelation, discussed important formulation parameters during the process, and summarized its applications in different sensitive bioactive substances. Finally, the development of this technique in the future was prospected.
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Keywords:
- emulsification/internal gelation /
- microcapsule /
- alginate /
- bioactive substances
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